Systems
Lead your lab to the forefront of Autoimmune diagnostics
Realize the full potential of multi-analyte testing with Aptiva’s Particle-based Multi-Analyte Technology (PMAT). With Aptiva®, streamline your workflow, deliver excellent clinical performance and diagnostic confidence.
Increase efficiency, enhance throughput, and improve your turnaround time
Generates up to 720 results per hour
Holds 150 primary patient tubes
6.5-hour consumable walkaway time
Time to first or STAT sample result/s
Time to next sample result/s
Advance patient care through increased diagnostic confidence
Autoimmune diagnosis is complex. Clinical symptoms vary, and often overlap with those of other diseases. For many patients with Autoimmune diseases, it may take years to receive a correct diagnosis and involve visits with up to 4 clinicians 1, 2, 3. Disease may progress before an accurate diagnosis can be made, and become more costly to treat 4, 5.
Aptiva delivers a more complete diagnostic profile to support clinical decision-making:
- Simultaneous detection of multiple autoantibodies improves diagnostic power
- Antibody profiles improve risk stratification and the probability of accurate diagnosis
- Supports clinical utility for better patient management 6, 7, 8
Intuitive touchscreen
Icon-driven software
Cuvette tower
Easily replenish during instrument operation
Dedicated probes
Eliminates carryover and improves throughput
Reagent carousel
Holds 20 cartridges
Sample bay
Holds 150 primary samples with continuous load in random access
Cuvette dry waste drawer
Ease of access
RFID reader
Records consumable identity
Realize the full potential of multi-analyte testing
Aptiva introduces PMAT to enable the simultaneous detection of multiple analytes from a single sample. PMAT improves workflow efficiencies by minimizing the need for additional runs and reducing sample requirements.
PMAT method
- Sample reactions for all analytes in each cartridge occur simultaneously
- Each analyte is associated with a unique signature
- Solid phase immunoassay uses fluorescence to quantify antibody levels
Reaction data is captured digitally
- Paramagnetic particles are aligned using magnets
- LEDs illuminate the particles
- The optical system captures high-resolution digital images
- Images are used to differentiate particles, and quantify antibody levels
Raw digital data storage capabilities
- Aptiva stores captured digital images in its database
- Results are generated on demand
Results on-demand
- Aptiva generates results on-demand based on LIS or clinician orders
- Future results can be generated from stored images without the need to reprocess samples or redraw the patient
1 Benaroya Research Institute. Diagnosing autoimmune diseases 2017. Available at: www.benaroyaresearch.org/blog/diagnosing-autoimmune-diseases
2 Sloan M et al. Medically explained symptoms: a mixed methods study of diagnostic, symptom and support experiences of patients with lupus and related systemic autoimmune diseases. Rheumatology Advances in Practice 2020
3 Fuchs V et al. Delayed celiac disease diagnosis predisposes to reduced quality of life and incremental use of health care services and medicines: a prospective nationwide study. United European Gastroenterol J 2018
4 Oglesby A et al. Impact of early versus late systemic lupus erythematosus diagnosis on clinical and economic outcomes. Applied health economics and health policy 2014
5 Fischer A et al. All-cause Healthcare Costs and Mortality in Patients with Systemic Sclerosis with Lung Involvement. The Journal of Rheumatology 2018
6 Laborde CM et al. Contribution of Multiplex Immunoassays to Rheumatoid Arthritis Management: From Biomarker Discovery to Personalized Medicine. J Pers Med 2020
7 Ahsan H. Monoplex and multiplex immunoassays: approval, advancements and alternatives. Comp Clin Path 2022
8 Bizzaro N et al. Multiparametric autoantibody analysis: a new paradigm for the diagnosis of connective tissue diseases. Arthritis Research & Therapy 2022
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sales.uk@werfen.com
Tel: 01925 810 141 - Option 6
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Tel: 0800 102 6342
service.uk@werfen.com
Tel: 01925 810 141 - Option 1