β2-microglobulin (β2m) is a component of major histocompatibility complex (MHC) class I molecules that is present in a majority of cells. As a biomarker, β2-microglobulin levels have usually been correlated with renal function. Abnormally high levels in urine alongside unusually high levels in blood are associated with renal failure beyond being a renal function marker, β2-microglobulin is also a type of tumor marker associated with multiple myeloma and chronic lymphocytic leukemia (CLL). In the case of multiple myeloma, serum β2m is included in the international staging system as a prognostic parameter alongside other parameters1. For chronic lymphocytic leukemia (CLL), β2-microglobulin is included in a prognostic model combined with other genetic, and clinical parameters to allow a more precise management of the disease2

How we can support you

Ready-to-use solutions in bulk for turbidimetric reagents

Whether you are planning a panel expansion for cancer-related parameters or aiming to enhance and secure your existing portfolio operations, our β2-microglobulin bulk reagent can support your needs. Our latex-based immunoassay for β2m ensures precise detection: when a sample containing β2m is mixed with the reagent, a distinct agglutination occurs, measurable by turbidimetry.

*Standardization, on board stability and linearity studies performed using an ILab Taurus analyzer (Werfen)

Our offering

Werfen’s β2-microglobulin bulk offering consists of the following products: